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OsteoPrime Ultra


Why use calcium and mineral formulas?
Calcium and other minerals are primary building blocks for bones.
Bone is living tissue and needs calcium and other important nutrients to support healthy bones and teeth, and support healthy bone density.† Since proper calcium intake can’t always be met through diet alone, a strong supplement can make a huge difference.

Why use OsteoPrime® Ultra?
It’s designed for important phases in women’s bone health.
OsteoPrime® Ultra bone formula delivers balanced nutrients to support and maintain healthy bones; including calcium for strong bones and teeth; magnesium to help form new calcium crystals; and zinc, vitamin C, and boron to help form the connective structures of the bone.

OsteoPrime® Ultra includes MenaQ7™.
This natto extract enhances calcium absorption and bone-building function.

OsteoPrime® Ultra uses clinically proven ingredients.
This combination uses ingredients proven to support healthy bones, increase bone density and reduce bone loss.

Directions: Take 4 tablets daily, during or after meals, or as recommended by your healthcare practitioner.
Serving Size: 4 Tablets Amount/Serving %DV
Calories 10

Total Carbohydrate 2g <1%**

Vitamin C (ascorbic acid) 120mg 200%

Vitamin D (as cholecalciferol) 800IU 200%

Vitamin K (as phytonadione) 300mcg 375%

Thiamin (as thiamin HCl) (vitamin B1) 20mg 1,333%

Riboflavin (vitamin B2) 20mg 1,176%

Niacin (as niacinamide) 50mg 250%

Vitamin B6 (as pyridoxine HCl) 25mg 1,250%

Folic Acid 800mcg 200%

Vitamin B12 (as cyanocobalamin) 50mcg 833%

Pantothenic Acid (as calcium D-pantothenate) 20mg 200%

Calcium (from calcium carbonate, tricalcium phosphate, calcium lactate, calcium Kreb’s cycle chelates**, and calcium citrate) 800mg 80%

Phosphorus (from tricalcium phosphate) 128mg 13%

Magnesium (as magnesium oxide and magnesium aspartate) 300mg 75%

Zinc (as zinc picolinate) 20mg 133%

Selenium (as sodium selenite) 100mcg 143%

Copper (as copper gluconate) 2mg 100%

Manganese (as manganese aspartate) 7mg 350%

Chromium (as chromium aspartate) 200mcg 167%

Molybdenum (as sodium molybdate) 50mcg 67%

Sodium 15mg <1%

Betaine HCl 20mg *

Strontium (as strontium chloride) 6mg *

Silicon (as sodium metasilicate) 5mg *

Boron (as boron Krebs cycle chelates) 3mg *

Vitamin K2 (menaquinone-7) from Natto (fermented soybean extract) 45mcg *

This product does not contain

    • artificial coloring
    • artificial flavoring
    • corn
    • gluten
    • preservatives
    • sugar
    • wheat
    • yeast
This product contains natural ingredients; color variations are normal.


If you are taking Coumadin®*** (warfarin) or other prescription drugs, or if pregnant or nursing, consult your healthcare practitioner before using this product.


Chelated as citrate, fumarate, malate, succinate, and alpha ketoglutarate.

***Trademark of its respective company.

Integrative Therapeutics’ evidence-based natural medicines are the only choice of doctors who rely on the fact base of premier science to deliver patient results.

**Based on 2000 calorie diet.

Other Ingredients

cellulose, modified cellulose gum, stearic acid, magnesium stearate, modified cellulose, silicon dioxide, vegetable glycerin, carnauba wax, and sodium caseinate (milk).

UPC Codes: 871791000247
Product Numbers: 206012, 70080, 76939

OsteoPrime® Ultra contains both strontium and calcium. Should these two minerals be taken together or will one interfere with the absorption of the other?

Dr. Alan Gaby, co-formulator of OsteoPrime® Ultra, comments:

To the best of my knowledge, the idea that strontium and calcium should not be taken together is theoretical, and not based on any clinical research. Some of the studies in which strontium therapy was beneficial did not separate the strontium from the calcium, or at least did not mention anything about whether or not they were taken together or apart. There are many nutrients that share the same absorption mechanism with other nutrients, but that does not mean they have to taken separately. Many foods contain both strontium and calcium, and the body seems to have figured out how to absorb them both.

It is possible (though I am not aware of any documentation) that, when giving massive doses of strontium, the absorption would be greater if calcium were not taken at the same time. However, there is evidence that high-dose strontium has significant adverse effects, including some adverse effects on bone. There is also evidence that lower doses of strontium may be more effective than higher doses, with respect to maintaining bone health. For those reasons, I am reluctant to recommend the high doses of strontium that some doctors claim should not be taken at the same time as calcium. The amount of strontium in OsteoPrime® Ultra is physiological (i.e., similar to the amount naturally occurring in food), and one might reasonably presume that the body’s normal absorption mechanisms would be able to handle both the strontium and calcium at the same time.

What’s the difference between Vitamin K and Natto K2 in this formula?

OsteoPrime® Ultra contains MenaQ7™, an exclusive, patented, highly bioavailable form of Vitamin K2. Clinical studies have shown that it enhances calcium absorption and bone building function.

In fact, one study compared the bioavailability and absorption rates between vitamin K2 and vitamin K1. For six weeks participants received either vitamin K1 or vitamin K2 (as menaquinon-7). Researchers then compared the levels of blood levels of vitamin K in both groups. They found that the participants who took natural vitamin K2 had much higher blood levels of vitamin K compared those receiving vitamin K1.

OsteoPrime® Ultra provides a balanced combination of important nutrients to support arterial health and maintain healthy bones.

Why so many types of calcium in this formula?

Simply put, more forms of calcium ensure more complete availability in the body. Each calcium salt—that is, each calcium attached to a different mineral—offers differing quantities of elemental calcium. Elemental calcium is the "bottom line" amount of calcium you absorb from food or a supplement. And while some calcium/mineral combinations have more elemental calcium than others, they’re not always easy to absorb. For example, calcium lactate is about 32 percent absorbed while calcium citrate is approximately 30 percent absorbed. Tricalcium phosphate is an important addition to the formula because is the most prevalent form of calcium in human bone.

Why does OsteoPrime® Ultra contain MK7 rather than MK4?

OsteoPrime® Ultra contains exclusive Natto K2 in the form of MK7 (methaquinone 7). MK7 is much more bioactive and bioavailable than MK4. However, MK4 has been shown to have very high benefits in high doses. The MK7 in OsteoPrime® Ultra can give the benefits needed in a smaller dose, and thus why it is easily put into a bone health supplement.

Dr Alan Gaby, the co-creator of OsteoPrime® Ultra, states the following in regards to MK7 vs. MK4:

  • MK4 is used in Japan in very high doses (45mg/day) for bone health support.
  • In studies MK7 in small doses had improved benefits in regards to bone health, whereas large doses of MK4 were needed.
  • Long-term safety has not been determined with MK4.
  • MK7 has a longer half-life (it lasts longer in the body).
    MK4 in small doses is of no significant value in helping to support bone health.
  • MK7 is the only form of vitamin K2 that is likely to have a beneficial effect when used in small doses.

Why would someone take OsteoPrime® Ultra instead of OsteoPrime®?

OsteoPrime® Ultra is an ultimate bone support product. OsteoPrime® Ultra is designed for women or men with significant bone support needs. It contains exclusive Natto K2 which diverts calcium away from the arteries to the bones. OsteoPrime® Ultra contains key minerals, such as strontium for increased bone strength, not found in other bone support supplements.

Can you tell me why the calcium products don’t mention that they need to be taken with food? I’ve heard that food improves absorption.

Calcium absorption varies based on many things, including the form of calcium as well as the presence of food in the digestive tract. While some research suggests that absorption might be a little better with food, it is not necessary to take calcium supplements with food to receive health benefits. If an individual has a sensitive stomach, we do recommend taking supplements with food to lessen the chance for stomach upset.


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"If we are creating ourselves all the time, then it is never too late to begin creating the bodies we want instead of the ones we mistakenly assume we are stuck with.”
― Deepak Chopra

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"The doctor of the future will no longer treat the human frame with drugs, but rather cure and prevent disease with nutrition"
Thomas Edison